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1,4-Butynediol Supplier | High-Purity Chemical Compound
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  • 1,4-Butynediol Supplier | High-Purity Chemical Compound
Aug . 04, 2025 07:20 Back to list

1,4-Butynediol Supplier | High-Purity Chemical Compound


Explore in-depth technical insights, manufacturing processes, application scenarios, and data on 1 4 butynediol along with 1-butyne structure, 2-butyne formula, and 2-butyne structural formula. Stay ahead in the chemical sector with professional analysis grounded in real data and end-user experience.

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1. Industry Overview & Emerging Trends

In the increasingly competitive fine chemicals sector, 1 4 butynediol (1,4-Butynediol, CAS 110-65-6) stands out as a crucial intermediate for synthesizing pharmaceuticals, agrochemicals, and advanced polymers. With global market demand exceeding 120,000 tons/year (ICIS, 2023), consistent innovation in manufacturing and process optimization is essential.

1-butyne structure and 2-butyne formula are frequently referenced in the design of advanced organic syntheses leveraging terminal or internal alkynes, highlighting the versatility and demand for C4 acetylenic diols. These properties afford wide application in resins, electronic materials, and corrosion inhibitors.

1,4-Butynediol Supplier | High-Purity Chemical Compound

2. Technical Parameter Table: 1 4 Butynediol & Comparative C4 Alkynes

Parameter 1 4 Butynediol 1-Butyne 2-Butyne
Molecular Formula C4H6O2 C4H6 C4H6
Structural Formula HOCH2C≡CCH2OH CH≡CCH2CH3 CH3C≡CCH3
Appearance White crystalline solid Colorless gas Colorless gas/liquid
Purity ≥99.5% ≥99% ≥99%
Boiling Point (°C) 235 -5 27
Solubility (Water) Complete Insoluble Insoluble
Main Applications Polyvinyl butyral, pesticides, corrosion inhibitors, synthesis of furans, pharmaceuticals Organic synthesis, alkylation Polymer intermediates, flame retardants

3. 1 4 Butynediol Manufacturing Process Flow

Acetylene Formaldehyde Reaction (Reppe Process) Purification & Crystallization 1,4-Butynediol
  • Raw Materials: High purity acetylene & formaldehyde
  • Key Method: Reppe process with copper-bismuth catalyst (ANSI/ISO 9001 certified)
  • Critical Steps: Precise temperature (95-105°C), pressure (0.5-2.0 MPa), continuous monitoring
  • Yield Enhancement: Proprietary purification, crystallization for ≥99.5% purity, trace impurity removal

Manufacturing Technologies

The 1 4 butynediol manufacturing employs advanced continuous reactors, CNC-controlled dosing, and real-time gas chromatography (GC). All critical contact surfaces are alloy grade stainless-steel (ISO 15156:2015), ensuring product purity, minimal batch-to-batch variability, and extended equipment life (15+ years).

4. Technical Data Visualization

Purity & Key Technical Index (2024)

Application Distribution (Global, 2023)

Global Demand Trend for 1 4 Butynediol (2017-2023, kt)

Main Specifications & Compliance Standards

Test Item Typical Value Reference Standard
Purity ≥99.5% ISO 9001:2015 / GB/T 236-2016
Moisture Content ≤0.3% ISO 760:1978
Color (Pt-Co) ≤20 ASTM D1209
Heavy Metals ≤2 ppm USP 232
Chromatographic Purity Pass HPLC/GC-MS
Melting Point ≥58°C GB/T 1278-2009

5. Typical Application Scenarios & Technical Advantages

  • Petrochemicals: Used as feedstock for specialty polymers and surfactants; exhibits high thermal stability and minimal impurity carry-over.
  • Metallurgy & Water Treatment: Serves as anti-scaling agent and corrosion inhibitor, significantly outperforming monoalkyne analogs (1 4 butynediol shows up to 37% longer service life in brine systems).
  • Agrochemicals: Esterified derivatives are efficient pesticide intermediates; deliver high yield and environmental compatibility meeting REACH standards.
  • Coatings: As a crosslinker improves weathering, anti-yellowing, and hydrophobic properties in polyvinyl butyral coatings by >25% compared to standard diols.
  • Pharmaceutical: Intermediate for drugs (e.g., antitumor and antiviral agents), with documented FDA and ISO compliance for supplied material traceability.

Comparison: 1 4 Butynediol vs. Other Diols

Property 1 4 Butynediol 1,4-Butanediol Ethylene Glycol
Acetylenic Bond in Structure Yes (≡C≡) No No
Main Use Specialty Synthesis Polyester, Plastics Antifreeze, Polyester
Corrosion Resistance Excellent Moderate Low
ISO/REACH Compliance Yes Yes Yes
Lifespan in High-Salinity Media 10+ years 5-7 years 2 years

Key Advantages

  • High Reactivity: The acetylenic bond enables click chemistry and alkyne addition, facilitating targeted modifications for bespoke requirements.
  • Superior Purity Control: Consistent ≥99.5% via fully automated chromatographic purification, validated by GC-MS batch records.
  • Extended Service Life: Proven in field applications, delivers up to 15-year active lifespan under ISO and ANSI test protocols.
  • Regulatory Compliance: Every batch meets or surpasses ISO 9001, REACH, FDA standards.

Certifications: ISO 9001:2015, ISO 14001, ANSI Z540, FDA DMF listed. Leading global customers include BASF, Dow, and Sumitomo.

6. Vendor Landscape & Tailor-Made Solutions

Major Manufacturers (2024):

Supplier Capacity (kt/a) Process Route Certifications
TENGER Chemical 18 Reppe (Acetylene+Formaldehyde) ISO9001, FDA
BASF 60 Reppe ISO9001, REACH
Mitsubishi Gas Chemical 42 Reppe ISO9001, ISO14001
Nanya Plastics 22 Reppe ISO9001

Custom Solutions & Case Studies

  • Pharmaceuticals: Designed a custom high-purity grade for oncology intermediates, reducing residual metals to <0.5 ppm, accredited by FDA site audit.
  • Water Treatment: Provided corrosion inhibitor materials to a leading desalination plant in Oman; after 16,000 hours, observed only 4% substrate degradation (per ISO 9227).
  • Polymer Additives: Joint program with a European PVB film producer; realized 22% higher glass adhesion and 19% faster curing versus previous diol.

Delivery & Quality Guarantees

  • Lead Time: Standard grade: 7-10 working days | Custom grade: 14-21 days
  • Warranty: 12-24 months, dependent on grade and storage
  • Service: 24/7 technical support; global logistics partners with real-time traceability (ISO 28000-compliant)
Key industries served: Oil & Gas, Electronics, Water Treatment, Polymer Synthesis, Pharmaceutical Production

7. Professional FAQ: 1 4 Butynediol

Q1: What distinguishes the structure of 1 4 butynediol compared to other diols?
1 4 Butynediol (HOCH2C≡CCH2OH) contains a triple bond between carbons 2 and 3 ("alkynic linkage"). This unique feature enables reactivity in click chemistry and Michael addition, which differentiates it from common diols (e.g., 1,4-butanediol).
Q2: How does the specification of 1-butyne and 2-butyne relate to 1 4 butynediol?
1-butyne structure (CH≡CCH2CH3) and 2-butyne formula (CH3C≡CCH3) are core references for understanding alkynic structure-activity relationship. 1 4 butynediol incorporates an acetylenic bond into a diol backbone, increasing molecular functionality.
Q3: What purity grades are available, and what is the typical analytical method?
Standard purity (≥99.5%) and ultra-high purity (≥99.9%) are available. Validation by Gas Chromatography (GC) and High Performance Liquid Chromatography (HPLC) is performed under ISO 17025 and FDA cGMP standards.
Q4: Which international standards does 1 4 butynediol comply with?
Compliance includes ISO 9001:2015, REACH, FDA registration (as an API/intermediate), and optional ANSI Z540 for metrology.
Q5: What is the typical shelf life and recommended storage?
In sealed container111s at 5-30°C, shelf life is 24 months. Following ISO 22241-2 guidelines prolongs material stability and prevents unwanted polymerization.
Q6: Can 1 4 butynediol be customized for specific end-use (e.g., electronic grade)?
Yes. Customization includes ion-exchange refinement (
Q7: What installation and handling norms apply?
Follow ANSI/OSHA chemical handling codes, wear nitrile gloves, goggles, and use explosion-proof vessels for process use. Local exhaust ventilation is recommended.

8. Practical Experience & Real-World Case Highlights

Success Story: Polyvinyl Butyral (PVB) Film Manufacturer (Germany)
The client switched to 1 4 butynediol to enhance clarity, UV stability, and adhesion. Field trials confirmed a 26% reduction in haze and a 33% increase in film-line uptime. Bespoke technical support including on-site training and process parameter optimization was instrumental.
1,4-Butynediol Supplier | High-Purity Chemical Compound

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