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  • To ensure that residual solvents are effectively monitored and controlled, good manufacturing practices (GMP) must be strictly followed. This includes optimizing the manufacturing process to minimize the use of solvents, selecting safer alternatives when possible, and implementing robust cleaning procedures. Additionally, regular testing of the final product is essential to confirm that solvent levels are within acceptable limits. Advanced analytical techniques such as gas chromatography (GC) are commonly employed to detect and quantify residual solvents in pharmaceutical formulations, ensuring compliance with regulatory standards.


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