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  • The classification of residual solvents is primarily based on their toxicity and potential risk to human health. The International Conference on Harmonisation (ICH) has categorized these solvents into three classes. Class 1 solvents are those that are prohibited due to their unacceptable toxicity, such as benzene and carbon tetrachloride. Class 2 solvents are limited because of their potential toxicity and include solvents like methanol and dichloromethane. Class 3 solvents are considered to have low toxic potential and are typically acceptable in pharmaceutical manufacturing, provided their levels are controlled and monitored.


  • In summary, formic acid is a compound of notable importance across various fields. Its diverse applications range from industrial to agricultural uses, and its biological significance cannot be overlooked. As we continue to explore sustainable methods and greener alternatives, formic acid may serve as a pivotal player in advancing science and industry while promoting ecological responsibility. Understanding and harnessing the potential of this simple yet powerful acid could pave the way for innovations that benefit both humans and the environment.